During his Angelus reflection, Pope Francis contemplates the personal trials he is enduring and highlights the "radiant signs of hope" that shine within hospitals and places of care.

Drawing from the mystery of the Transfiguration, he reflects on how Jesus, immersed in prayer, becomes luminous with divine light, revealing to His disciples the infinite love behind His actions. Inspired by this, Pope Francis acknowledges the shared suffering of those who are ill, affirming that despite physical weakness, nothing can hinder love, prayer, and acts of kindness that serve as beacons of hope for one another.

The Pope underscores the "light" present in hospitals and caregiving spaces, where even the simplest acts of service radiate love. He encourages everyone to join him in praising God, who never abandons His people and who, in times of hardship, places compassionate individuals in their lives as reflections of His love.

Expressing gratitude for the prayers offered on his behalf—especially from children, some of whom visited him at Gemelli Hospital—Pope Francis reassures them of his love and eagerness to see them.

He concludes his address with prayers for global peace, particularly in war-stricken regions like Ukraine, Palestine, Israel, Lebanon, Myanmar, Sudan, and the Democratic Republic of Congo. Additionally, he calls for prayers for the Church as it advances through the synodal journey's implementation phase.